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B.1-3 Lifespan. "If Bipolar Disorder Is Over-diagnosed, What Are The Actual Diagnoses?." ScienceDaily. ScienceDaily, 29 July 2009. <www.sciencedaily.com/releases/2009/07/090729100936.htm>.
B4. Rashmi Patel et al. Mood instability is a common feature of mental health disorders and is associated with poor clinical outcomes.BMJ Open, May 2015 DOI: 10.1136/bmjopen-2014-007504
King's College London. "Mood instability common to mental health disorders, associated with poor outcomes." ScienceDaily. ScienceDaily, 21 May 2015. <www.sciencedaily.com/releases/2015/05/150521210637.htm>.
C.1 H M Chen, C J DeLong, M Bame, I Rajapakse, T J Herron, M G McInnis, K S O’Shea. Transcripts involved in calcium signaling and telencephalic neuronal fate are altered in induced pluripotent stem cells from bipolar disorder patients. Translational Psychiatry, 2014; 4 (3): e375 DOI: 10.1038/tp.2014.12
University of Michigan Health System. "First stem cell study of bipolar disorder yields promising results." ScienceDaily. ScienceDaily, 25 March 2014. <www.sciencedaily.com/releases/2014/03/140325113226.htm>.
C.2 Glenn T. Konopaske, Nicholas Lange, Joseph T. Coyle, Francine M. Benes. Prefrontal Cortical Dendritic Spine Pathology in Schizophrenia and Bipolar Disorder. JAMA Psychiatry, 2014; DOI:10.1001/jamapsychiatry.2014.1582
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C.3 Children vs adults
Ezra Wegbreit, Grace K. Cushman, Megan E. Puzia, Alexandra B. Weissman, Kerri L. Kim, Angela R. Laird, Daniel P. Dickstein.Developmental Meta-analyses of the Functional Neural Correlates of Bipolar Disorder. JAMA Psychiatry, 2014; DOI:10.1001/jamapsychiatry.2014.660
Lifespan. "Difference found in way bipolar disorder affects brains of children versus adults." ScienceDaily. ScienceDaily, 18 June 2014. www.sciencedaily.com/releases/2014/06/140618165113.htm
C.3 MRI scans and Lithium.
C P Johnson, R L Follmer, I Oguz, L A Warren, G E Christensen, J G Fiedorowicz, V A Magnotta, J A Wemmie. Brain abnormalities in bipolar disorder detected by quantitative T1%u03C1 mapping.Molecular Psychiatry, 2015; DOI: 10.1038/mp.2014.157
University of Iowa Health Care. "Bipolar disorder: New MRI imaging provides new picture, new insight." ScienceDaily. ScienceDaily, 6 January 2015. <www.sciencedaily.com/releases/2015/01/150106081217.htm>.
C.4 Wael El-Deredy et al. Decision-making and trait impulsivity in bipolar disorder are associated with reduced prefrontal regulation of striatal reward valuation. Brain, July 2014 DOI: 10.1093/brain/awu152
Manchester University. "Why people with bipolar disorder are bigger risk-takers." ScienceDaily. ScienceDaily, 9 July 2014. <www.sciencedaily.com/releases/2014/07/140709095626.htm>.
D.1David Gurwitz et al. Insulin-like Growth Factor 1 Differentially Affects Lithium Sensitivity of Lymphoblastoid Cell Lines from Lithium Responder and Non-responder Bipolar Disorder Patients. Journal of Molecular Neuroscience, April 2015 DOI: 10.1007/s12031-015-0523-8
American Friends of Tel Aviv University. "Personalizing bipolar disorder treatment." ScienceDaily. ScienceDaily, 22 April 2015. <www.sciencedaily.com/releases/2015/04/150422121911.htm>.
D.2Steven H. Jones, Gina Smith, Lee Mulligan, Fiona Lobban, Heather Law, Graham Dunn, Mary Welford, James Kelly, John Mulligan And Anthony P. Morrison. Recovery-focused cognitive-behavioural therapy for recent-onset bipolar disorder: randomised controlled pilot trial.British Journal of Psychiatry, September 2014 DOI:10.1192/bjp.bp.113.141259
Lancaster University. "Talking therapy for people with a recent bipolar disorder diagnosis." ScienceDaily. ScienceDaily, 11 September 2014. <www.sciencedaily.com/releases/2014/09/140911093328.htm>.
D.3Haiming Chen, Nulang Wang, Xin Zhao, Christopher A Ross, K Sue O’Shea, Melvin G McInnis. Gene expression alterations in bipolar disorder postmortem brains. Bipolar Disorders, 2013; 15 (2): 177 DOI:10.1111/bdi.12039
niversity of Michigan Health System. "Do drugs for bipolar disorder 'normalize' brain gene function?." ScienceDaily. ScienceDaily, 11 April 2013. <www.sciencedaily.com/releases/2013/04/130411105833.htm>.
E.1Robert A Power, Stacy Steinberg, et.al, Polygenic risk scores for schizophrenia and bipolar disorder predict creativity. Nature Neuroscience, 2015; DOI:10.1038/nn.4040
King's College London. "Schizophrenia, bipolar disorder may share genetic roots with creativity." ScienceDaily. ScienceDaily, 8 June 2015. <www.sciencedaily.com/releases/2015/06/150608120145.
E.2 Mark Weise et al. Biological insights from 108 schizophrenia-associated genetic loci. Nature, 2014; 511 (7510): 421 DOI:10.1038/nature13595
Niamh L. O’Brien, et.al, The functional GRM3 Kozak sequence variant rs148754219 affects the risk of schizophrenia and alcohol dependence as well as bipolar disorder. Psychiatric Genetics, 2014; 1 DOI: 10.1097/YPG.0000000000000050
University College London. "Gene variant linked to schizophrenia, bipolar disorder, alcoholism." ScienceDaily. ScienceDaily, 22 July 2014. www.sciencedaily.com/releases/2014/07/140722091611.htm
E.3Thomas W. Mühleisen, et.al, Genome-wide association study reveals two new risk loci for bipolar disorder.Nature Communications, 2014; 5 DOI: 10.1038/ncomms4339
Universität Bonn. "New gene for bipolar disorder discovered." ScienceDaily. ScienceDaily, 11 March 2014. <www.sciencedaily.com/releases/2014/03/140311123919.htm>.
F1. Elizabeth Tyler, Steven Jones, Nancy Black, Lesley-Anne Carter, Christine Barrowclough. The Relationship between Bipolar Disorder and Cannabis Use in Daily Life: An Experience Sampling Study.PLOS ONE, 2015; 10 (3): e0118916 DOI: 10.1371/journal.pone.0118916
Lancaster University. "How cannabis use affects people with Bipolar Disorder." ScienceDaily. ScienceDaily, 13 March 2015. <www.sciencedaily.com/releases/2015/03/150313130855.htm>.
F.2 Melanie Gibbs, Catherine Winsper, Steven Marwaha, Eleanor Gilbert, Matthew Broome, Swaran P. Singh. Cannabis use and mania symptoms: A systematic review and meta-analysis. Journal of Affective Disorders, 2015; 171: 39 DOI: 10.1016/j.jad.2014.09.016
University of Warwick. "Significant link between cannabis use and onset of mania symptoms." ScienceDaily. ScienceDaily, 10 February 2015. <www.sciencedaily.com/releases/2015/02/150210160101.htm>.
G. K.Ryan, et.al, Shared dimensions of performance and activation dysfunction in cognitive control in females with mood disorders. Brain, 2015; 138 (5): 1424 DOI:10.1093/brain/awv070
University of Michigan Health System. "'Fuzzy thinking' in depression, bipolar disorder: New research finds effect is real." ScienceDaily. ScienceDaily, 4 May 2015. <www.sciencedaily.com/releases/2015/05/150504171055.htm>.
H. Biblical Counseling Coalition website, Sept.7, 2015. Medication Biblical Counseling, & Depression: What’s New in Serotonin. Charles Hodges MD